Description

1-Bromo-4-Fluoro-2-Trifluoromethoxy-Benzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a trifluoromethoxy group, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Material Science Research: Employed in creating novel polymers and ligands with tailored properties for catalysis and advanced material applications.

Basic Information

Product Name	1-Bromo-4-Fluoro-2-Trifluoromethoxy-Benzene
CAS No.	1242252-07-8
Molecular Formula	C7H3BrF4O
Molecular Weight	259.00 g/mol
Synonyms	2-Bromo-5-fluoro-1-(trifluoromethoxy)benzene; 4-Fluoro-2-(trifluoromethoxy)bromobenzene; 1-Bromo-4-fluoro-2-(trifluoromethoxy)benzene; 2-Bromo-5-fluoroanisole, α,α,α-trifluoro-; Benzene, 1-bromo-4-fluoro-2-(trifluoromethoxy)-; 5-Fluoro-2-(trifluoromethoxy)bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoro-2-Trifluoromethoxy-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and support your regulatory documentation needs for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.