Description

4-(Ethoxycarbonyl)Pyridine-2-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound is a versatile reagent prized for its stability and reactivity in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized pyridine cores.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable boronic ester reagent for forming carbon-carbon bonds with aryl/heteroaryl halides, a fundamental transformation in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate pyridine-based structures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: A precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems and target engagement.

Basic Information

Product Name	4-(Ethoxycarbonyl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1241898-91-8
Molecular Formula	C14H20BNO4
Molecular Weight	277.12 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isonicotinic acid ethyl ester; Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate; 4-(Ethoxycarbonyl)-2-pyridineboronic acid pinacol ester; Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isonicotinate; Isonicotinic acid, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-(Ethoxycarbonyl)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) are available for every batch upon request, confirming compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.