Description

2-[1-(3-Fluorophenyl)Vinyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex fluorinated aromatic compounds, which are critical motifs in advanced material and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for introducing the 3-fluorostyryl moiety into complex molecules, enabling carbon-carbon bond formation under mild conditions.
• Pharmaceutical Intermediate Synthesis: Serves as a critical building block in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Active Ingredient Development: Used to synthesize novel herbicides, fungicides, and insecticides that leverage the stability and bioavailability of fluorinated aromatic structures.
• Material Science & OLED Research: Employed in the synthesis of fluorinated organic semiconductors, light-emitting materials, and other advanced electronic materials for enhanced performance.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized to create fluorescent tags, molecular probes, and other tools for studying biological systems and mechanisms.

Basic Information

Product Name	2-[1-(3-Fluorophenyl)Vinyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1239700-55-0
Molecular Formula	C₁₄H₁₈BFO₂
Molecular Weight	248.10 g/mol
Synonyms	(3-Fluorophenyl)ethenylboronic acid pinacol ester; 1-(3-Fluorophenyl)vinylboronic acid pinacol ester; 3-Fluorostyrylboronic acid pinacol ester; Pinacol (3-fluorostyryl)boronate; (3-Fluorostyryl)boronic acid pinacol ester; 2-[(E)-2-(3-Fluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-(2-(3-Fluorophenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1239700-55-0
EINECS	Contact for details

Quality Control

Our 2-[1-(3-Fluorophenyl)Vinyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistent performance for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring full traceability and compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomer Content (GC/HPLC)	Reported on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.