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[3-(1H-Pyrazol-3-Yl)Phenyl]Boronic Acid CAS NO 1238377-35-9


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CAS No.:1238377-35-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[3-(1H-Pyrazol-3-Yl)Phenyl]Boronic Acid is a high-purity, functionalized boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl compounds, which are core structures in many drug candidates.
  • Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its ability to form carbon-carbon bonds under mild conditions.
  • Material Science: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, due to its conjugated pyrazole-phenyl system.
  • Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes targeting proteins of interest.
  • Ligand Synthesis: Serves as a starting material for preparing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
  • Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name [3-(1H-Pyrazol-3-Yl)Phenyl]Boronic Acid
CAS No. 1238377-35-9
Molecular Formula C9H9BN2O2
Molecular Weight 188.00 g/mol
Synonyms (3-(1H-Pyrazol-3-yl)phenyl)boronic acid; 3-(1H-Pyrazol-3-yl)benzeneboronic acid; B-[3-(1H-Pyrazol-3-yl)phenyl]boronic acid; (3-(1H-Pyrazol-3-yl)phenyl)boronic acid pinacol ester (protected form); 3-Pyrazolylphenylboronic acid; 3-(1H-Pyrazol-3-yl)phenylboronic acid; Boronic acid, B-[3-(1H-pyrazol-3-yl)phenyl]-
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Quality Control

Our [3-(1H-Pyrazol-3-Yl)Phenyl]Boronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements of research and process chemistry. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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