Description

4-Chloro-2-Hydroxyphenylboronic Acid is a versatile and synthetically valuable organoboron building block. This compound matters for its crucial role as a key intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, including kinase inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides by enabling the formation of complex biaryl structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and other advanced chemical processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Item	Detail
Product Name	4-Chloro-2-Hydroxyphenylboronic Acid
CAS No.	1238196-66-1
Molecular Formula	C6H6BClO3
Molecular Weight	172.37 g/mol
Synonyms	(4-Chloro-2-hydroxyphenyl)boronic acid; 2-Hydroxy-4-chlorobenzeneboronic acid; 4-Chloro-2-hydroxybenzeneboronic acid; Boronic acid, B-(4-chloro-2-hydroxyphenyl)-; 4-Chloro-2-hydroxy phenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Hydroxyphenylboronic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.