Description

1,3,2-Dioxaborolane, 2-(4-Iodobutyl)-4,4,5,5-Tetramethyl- is a high-value organoboron building block featuring a reactive iodoalkyl chain. This compound is essential for advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile electrophilic partner for the palladium-catalyzed formation of carbon-carbon bonds with aryl/vinyl boronic acids.
• Pharmaceutical Intermediate Synthesis: A key precursor in the development of novel drug candidates, especially for creating biaryl and alkyl-aryl linked structures.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and insecticides that require specific boron-containing motifs.
• Polymer & Materials Science: Employed in the synthesis of functionalized polymers, dendrimers, and organic electronic materials.
• Radiolabeling Precursor: The iodine moiety provides a potential handle for introducing radioactive isotopes (e.g., I-125) for imaging and diagnostic applications.
• Ligand & Catalyst Development: Useful for constructing sophisticated chelating ligands and organometallic catalysts.

Basic Information

Item	Detail
Product Name	1,3,2-Dioxaborolane, 2-(4-Iodobutyl)-4,4,5,5-Tetramethyl-
CAS No.	1236275-93-6
Molecular Formula	C10H20BIO2
Molecular Weight	310.98 g/mol
Synonyms	2-(4-Iodobutyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(4-iodobutyl)-1,3,2-dioxaborolane; (4-Iodobutyl)boronic acid pinacol ester; 4-Iodobutylboronic acid pinacol ester; Pinacol (4-iodobutyl)boronate; 1,3,2-Dioxaborolane, 2-(4-iodobutyl)-4,4,5,5-tetramethyl-; 4-Iodobutyl-Bpin
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-(4-Iodobutyl)-4,4,5,5-Tetramethyl- is manufactured under strict quality protocols. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 11B), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full specification data are provided for every shipment, supporting your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.