Description

4-Methylpyridine-2-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyridine-containing active pharmaceutical ingredients (APIs) and drug candidates via cross-coupling.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides that incorporate functionalized pyridine motifs.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands for transition metal catalysis and organometallic complexes.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and molecular architectures.
• Custom Synthesis: Provides a handle for the modular introduction of the 4-methylpyridin-2-yl group into complex target molecules.

Basic Information

Product Name	4-Methylpyridine-2-Boronic Acid Pinacol Ester
CAS No.	1236119-88-2
Molecular Formula	C₁₂H₁₈BNO₂
Molecular Weight	219.09 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylpyridine; 4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Methylpyridine-2-boronic acid pinacol ester; 4-Methyl-2-pyridineboronic acid pinacol ester; 2-(4-Methylpyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 4-Methylpyridine-2-boronate
EINECS	Contact for details

Quality Control

Our 4-Methylpyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.