Description

2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl Acetate is a high-purity, synthetically valuable organoboron reagent. This compound is a protected benzylboronic ester derivative, offering enhanced stability and handling properties for advanced organic synthesis. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling key carbon-carbon bond-forming reactions like the Suzuki-Miyaura cross-coupling.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or substituted benzyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed as a tool compound or linker in the development of enzyme inhibitors, probes, and bioconjugation strategies.
• Catalyst & Ligand Development: Used to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl Acetate
CAS No.	1235451-03-2
Molecular Formula	C15H21BO4
Molecular Weight	276.14 g/mol
Synonyms	Benzyl Acetate, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-; (Acetoxymethyl)phenylboronic acid pinacol ester; 2-(Acetoxymethyl)phenylboronic Acid Pinacol Ester; (2-(Acetoxymethyl)phenyl)boronic Acid Pinacol Ester; Pinacol (2-(Acetoxymethyl)phenyl)boronate; Benzylboronic Acid Pinacol Ester Acetate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized; allow the sealed container to reach room temperature before opening to minimize moisture ingress and oxidative degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.