Description

Cyclobutanepropanenitrile, 3,3-Difluoro-β-Oxo- is a high-value, fluorinated organic building block characterized by its reactive nitrile and ketone functional groups on a cyclobutane scaffold. This compound is critical for advanced synthetic chemistry, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for incorporating fluorinated cyclobutane motifs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the difluoro and nitrile groups enhance biological activity and stability.
• Material Science: Employed in the creation of specialty polymers and advanced organic materials with tailored electronic or physical properties.
• Chemical Synthesis: Acts as a versatile building block for organic synthesis, including cycloaddition reactions and the preparation of complex heterocycles.
• Fluorine Chemistry: A valuable substrate for further fluorination or functionalization studies in organofluorine chemistry research.

Basic Information

Product Name	Cyclobutanepropanenitrile, 3,3-Difluoro-β-Oxo-
CAS No.	1234616-26-2
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	3,3-Difluoro-2-oxocyclobutanepropanenitrile; 3,3-Difluoro-β-oxocyclobutanepropanenitrile; 2-(2-Cyanoethyl)-3,3-difluorocyclobutanone; 3,3-Difluoro-1-(2-cyanoethyl)cyclobutan-2-one; (3,3-Difluoro-2-oxocyclobutyl)acetonitrile
EINECS	Contact for details

Quality Control

Our production of Cyclobutanepropanenitrile, 3,3-Difluoro-β-Oxo- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.