Description

(S,E)-3-((E)-2-((1R,3As,7Ar)-1-((R)-6-Hydroxy-6-Methylheptan-2-Yl)-7A-Methylhexahydro-1H-Inden-4(2H)-Ylidene)Ethylidene)-4-Methylenecyclohexanol is a high-purity, synthetically derived steroidal intermediate of significant interest in advanced pharmaceutical research and development. Its complex, defined stereochemistry makes it a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology. This compound is essential for R&D chemists and process development scientists working on next-generation steroid-based pharmaceuticals, where precise molecular structure is paramount for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potent steroid hormone analogs and modulators.
• Research & Development: Used in academic and industrial laboratories for investigating structure-activity relationships (SAR) of steroidal compounds.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs) with steroidal backbones.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool Compound: Utilized in biological assays to study steroid receptor interactions and signaling pathways.

Basic Information

Product Name	(S,E)-3-((E)-2-((1R,3As,7Ar)-1-((R)-6-Hydroxy-6-Methylheptan-2-Yl)-7A-Methylhexahydro-1H-Inden-4(2H)-Ylidene)Ethylidene)-4-Methylenecyclohexanol
CAS No.	1233749-00-2
Molecular Formula	C25H40O2
Molecular Weight	372.59 g/mol
Synonyms	4-Methylene-3-[(1E,3E)-4-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]but-1-en-2-yl]cyclohexan-1-ol; Steroidal Diene Intermediate; (22R)-26-Hydroxy-27-nor-5α-cholesta-1,3,23-triene; Advanced Steroid Synthesis Intermediate
EINECS	Contact for details

Quality Control

Every batch of our (S,E)-3-((E)-2-((1R,3As,7Ar)-1-((R)-6-Hydroxy-6-Methylheptan-2-Yl)-7A-Methylhexahydro-1H-Inden-4(2H)-Ylidene)Ethylidene)-4-Methylenecyclohexanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development work. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (HPLC, NMR, MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive (store away from light). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Optical Rotation	Specific range provided per COA
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.