Description

N,2-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis. CAS No. 1233526-90-3.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic structures.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs or organic photovoltaics.
• Chemical Research: An indispensable reagent in academic and industrial R&D labs for constructing complex molecular architectures via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Custom Synthesis: Provides a versatile handle for the late-stage functionalization of complex molecules in contract research and manufacturing.

Basic Information

Item	Detail
Product Name	N,2-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	1233526-90-3
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,2-dimethylbenzamide; 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-methylbenzamide; 4-Pinacolatoboryl-N,2-dimethylbenzamide; N,2-Dimethyl-4-(pinacolatoboryl)benzamide; 4-Boronic acid, N,2-dimethylbenzamide, pinacol ester
EINECS	Contact for details

Quality Control

Every batch of N,2-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide undergoes rigorous analytical testing to ensure it meets the high standards required for sensitive cross-coupling reactions. Our quality assurance protocols include HPLC, NMR, and MS analysis to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and hydrolysis. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.