Description

1-(Cyclobutylmethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. Pharmaceutical, agrochemical, and advanced materials researchers need it for the discovery and development of new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring complex pyrazole-boronate structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is crucial.
• Chemical Biology & Bioconjugation: Acts as a versatile handle for labeling biomolecules or creating chemical probes for diagnostic and research applications.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Item	Details
Product Name	1-(Cyclobutylmethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1233526-47-0
Molecular Formula	C₁₄H₂₃BN₂O₂
Molecular Weight	262.16 g/mol
Synonyms	1-(Cyclobutylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(cyclobutylmethyl)-1H-pyrazole; 1-(Cyclobutylmethyl)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; Pyrazole boronic acid pinacol ester derivative; Cyclobutylmethyl pyrazole boronate; B-(1-(Cyclobutylmethyl)-1H-pyrazol-4-yl)boronic acid pinacol ester; CAS 1233526-47-0
EINECS	Contact for details

Quality Control

Our 1-(Cyclobutylmethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to minimize exposure to moisture and oxygen, which can affect stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.