Description

1-Ethyl-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile and stable intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazole heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific pyrazole-boronate structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation tools due to its selective reactivity.
• Catalyst & Ligand Development: Utilized in the preparation of novel catalysts and ligands for transition metal-catalyzed processes.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses producing specialty and fine chemicals for diverse clients.

Basic Information

Product Name	1-Ethyl-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1233525-88-6
Molecular Formula	C11H21BN2O2
Molecular Weight	224.11 g/mol
Synonyms	1-Ethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Ethyl-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Ethyl-3-pyrazoleboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-ethyl-1H-pyrazole; Pyrazole-3-boronic acid pinacol ester, 1-ethyl-; 1-Ethyl-1H-pyrazole-3-boronic acid pinacol ester; 1-Ethyl-3-(pinacolboryl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1-Ethyl-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.