Description

1,2-Di-o-Butyryl-Myo-Inositol 3,4,5,6-Tetrakisphosphate-Octakis(Propionoxymethyl) Ester is a sophisticated, cell-permeable derivative of inositol polyphosphate, designed for advanced biochemical and pharmacological research. This compound is a critical tool for studying intracellular signaling pathways, particularly those involving inositol phosphates as second messengers. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, cell biology, and drug discovery for probing calcium release and cellular communication mechanisms.

Application

• Biochemical Research: As a cell-permeable precursor for the controlled intracellular delivery of inositol polyphosphates (e.g., InsP4, InsP6) to study their roles in calcium signaling and cellular regulation.
• Neuroscience Studies: Investigation of synaptic transmission, neuronal plasticity, and receptor-mediated signaling cascades within neural tissues.
• Pharmacology & Drug Discovery: Used as a research tool to screen and validate novel therapeutic targets related to phosphoinositide pathways in various disease models.
• Cell Biology: Probing intracellular messenger systems, membrane trafficking, and enzyme kinetics related to inositol phosphate metabolism.
• Signal Transduction Analysis: Facilitating the study of G-protein coupled receptor (GPCR) pathways and other receptor-mediated cellular responses.

Basic Information

Product Name	1,2-Di-o-Butyryl-Myo-Inositol 3,4,5,6-Tetrakisphosphate-Octakis(Propionoxymethyl) Ester
CAS No.	1233512-98-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	InsP4 Octakis(Propionoxymethyl) Ester; 1,2-Di-O-butyryl-myo-inositol 3,4,5,6-tetrakisphosphate octakis(propionoxymethyl) ester; Cell-permeable InsP4 analogue; myo-Inositol 3,4,5,6-tetrakisphosphate, 1,2-di-O-butyryl-, octakis(propionoxymethyl) ester; Inositol polyphosphate prodrug; IP4-Octa-POM ester
EINECS	Contact for details

Quality Control

Our high-purity biochemical reagents are manufactured under strict quality control protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.