Description

N,n-Dimethyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organoboron building block. This compound is critical for facilitating efficient cross-coupling reactions, particularly in the synthesis of complex molecules for drug discovery and material science. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for constructing biaryl and heterobiaryl structures in active pharmaceutical ingredient (API) synthesis.
• Pharmaceutical Intermediate: Serves as a crucial building block in the development of novel therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and conductive films.
• Chemical Biology & Proteomics: Acts as a functional handle for bioconjugation and the development of chemical probes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, functionalized aniline derivatives.

Basic Information

Product Name	N,n-Dimethyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline Hydrochloride
CAS No.	1231967-65-9
Molecular Formula	C14H23BClNO2
Molecular Weight	283.60 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylaniline hydrochloride; N,N-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine hydrochloride; 3-Dimethylaminophenylboronic acid pinacol ester hydrochloride; (3-(Dimethylamino)phenyl)boronic acid pinacol ester hydrochloride; B-(3-(Dimethylamino)phenyl)boronic acid pinacol ester HCl
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in cGMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.