Description

2-(2-Nitrophenyl)-Thiazolo[5,4-B]Pyridine-6-Carboxylic Acid Methyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing novel heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Material Science Precursor: Can be utilized in the development of organic electronic materials or advanced polymers due to its conjugated thiazolopyridine core.
• Chemical Biology Probes: Acts as a starting material for creating fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical entity.

Basic Information

Product Name	2-(2-Nitrophenyl)-Thiazolo[5,4-B]Pyridine-6-Carboxylic Acid Methyl Ester
CAS No.	1231952-70-7
Molecular Formula	C16H11N3O4S
Molecular Weight	341.34 g/mol
Synonyms	Methyl 2-(2-nitrophenyl)thiazolo[5,4-b]pyridine-6-carboxylate; Thiazolo[5,4-b]pyridine-6-carboxylic acid, 2-(2-nitrophenyl)-, methyl ester; 2-(2-Nitrophenyl)thiazolo[5,4-b]pyridine-6-methyl carboxylate; 1231952-70-7; Methyl 2-(o-nitrophenyl)thiazolo[5,4-b]pyridine-6-carboxylate
EINECS	Contact for details

Quality Control

Our 2-(2-Nitrophenyl)-Thiazolo[5,4-B]Pyridine-6-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.