Description

3-Methyl-6-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and production of new pesticides, herbicides, and fungicides with improved efficacy and selectivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials and emissive layer components in advanced display technologies.
• Polymer & Materials Science: Incorporated into specialty polymers and organic frameworks to modify electronic properties, thermal stability, and mechanical strength.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for diagnostic and biochemical research applications.
• Catalyst & Ligand Synthesis: Serves as a starting material for the preparation of novel ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Methyl-6-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	1231934-47-6
Molecular Formula	C16H22BN3O2
Molecular Weight	299.18 g/mol
Synonyms	3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[4,3-a]pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-[1,2,4]triazolo[4,3-a]pyridine; 3-Methyl-6-(pinacolboryl)-[1,2,4]triazolo[4,3-a]pyridine; [1,2,4]Triazolo[4,3-a]pyridine, 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1231934-47-6; 3-Methyl-6-(pinacolatoboryl)-[1,2,4]triazolo[4,3-a]pyridine; 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,4-triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our 3-Methyl-6-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support cGMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.