Description

n-Methyl-n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is a high-purity, synthetically valuable boronic ester derivative, serving as a critical building block in modern organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science Research: Building block for creating organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of bioconjugation reagents and molecular probes for studying biological processes.
• Academic & R&D Laboratories: Essential reagent for methodological development in synthetic organic chemistry and catalysis research.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of bespoke, complex organic molecules on a commercial scale.

Basic Information

Product Name	n-Methyl-n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide
CAS No.	1231257-90-1
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	N-Methyl-N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide; 3-(N-Methylacetamido)phenylboronic acid pinacol ester; 1-Methyl-1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide; Acetamide, N-methyl-N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 3-Acetamido-N-methylphenylboronic acid pinacol ester; B-[3-(N-Methylacetamido)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our n-Methyl-n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.