Description

5-Bromo-2-Methylphenylacetonitrile is a versatile brominated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive cyano group and a bromine substituent on a methylated phenyl ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional polymers.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry optimization in laboratory settings.

Basic Information

Product Name	5-Bromo-2-Methylphenylacetonitrile
CAS No.	1231244-85-1
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	2-(5-Bromo-2-methylphenyl)acetonitrile; (5-Bromo-2-methylphenyl)acetonitrile; 5-Bromo-o-tolylacetonitrile; α-Cyano-5-bromo-2-methyltoluene; 2-Methyl-5-bromophenylacetonitrile; 5-Bromo-2-methylbenzyl cyanide
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methylphenylacetonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We are committed to meeting the stringent requirements of research and cGMP-grade production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.