Description

1H-Imidazole, 2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-value, functionalized boronic ester derivative of imidazole, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling the efficient synthesis of complex molecules through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with specific targeting properties.
• Material Science Research: Building block for creating novel organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic synthesis and catalysis studies.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis under cGMP guidelines for pharmaceutical production.

Basic Information

Product Name	1H-Imidazole, 2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	1229584-17-1
Molecular Formula	C15H19BN2O2
Molecular Weight	270.14 g/mol
Synonyms	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-imidazole; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]imidazole; 4-(1H-Imidazol-2-yl)phenylboronic acid pinacol ester; (4-(1H-Imidazol-2-yl)phenyl)boronic acid pinacol ester; 2-(4-Boronophenyl)imidazole pinacol ester
EINECS	Contact for details

Quality Control

Our 1H-Imidazole, 2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with specifications that can meet research, technical, and pharmaceutical grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.