Description

3-(Benzyloxy)-5-Chlorobenzaldehyde is a versatile aromatic aldehyde building block characterized by its benzyl-protected phenolic oxygen and reactive formyl group. This compound matters for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the chlorobenzene moiety for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the aldehyde group facilitates further condensation reactions.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A high-purity building block supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-(Benzyloxy)-5-Chlorobenzaldehyde
CAS No.	1228956-94-2
Molecular Formula	C14H11ClO2
Molecular Weight	246.69 g/mol
Synonyms	5-Chloro-3-(phenylmethoxy)benzaldehyde; 5-Chloro-3-benzyloxybenzaldehyde; 3-Benzyloxy-5-chlorobenzaldehyde; Benzaldehyde, 5-chloro-3-(phenylmethoxy)-; 3-(Benzyloxy)-5-chlorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-(Benzyloxy)-5-Chlorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.