Description

1-Bromo-3-Chloro-2,4-Dimethoxybenzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen and methoxy functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromo and chloro substituents are crucial for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where methoxy and halogen groups tune electronic properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological mechanisms and interactions.
• Custom Synthesis and Scale-up: A versatile substrate for contract research organizations (CROs) and CDMOs performing custom synthesis from milligram to kilogram scale.

Basic Information

Product Name	1-Bromo-3-Chloro-2,4-Dimethoxybenzene
CAS No.	1228956-93-1
Molecular Formula	C8H8BrClO2
Molecular Weight	251.51 g/mol
Synonyms	2,4-Dimethoxy-1-bromo-3-chlorobenzene; 3-Chloro-1-bromo-2,4-dimethoxybenzene; Benzene, 1-bromo-3-chloro-2,4-dimethoxy-; 1-Bromo-3-chloro-2,4-dimethoxy-benzene
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-3-Chloro-2,4-Dimethoxybenzene is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your project specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.