Description

1-Chloro-3-(Chloromethyl)-5-(Trifluoromethyl)Benzene is a versatile and high-value halogenated aromatic building block, essential for advanced chemical synthesis. Its molecular structure, featuring both chloromethyl and trifluoromethyl substituents, makes it a critical precursor for introducing specific functional groups into target molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules requiring chloromethyl and trifluoromethyl phenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Functional Material Development: Employed in the creation of monomers and polymers for advanced materials with specific electronic or surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex molecular architectures.
• Life Science Research: Acts as a chemical probe or labeling reagent in biochemical and medicinal chemistry research programs.

Basic Information

Product Name	1-Chloro-3-(Chloromethyl)-5-(Trifluoromethyl)Benzene
CAS No.	1228898-69-8
Molecular Formula	C8H5Cl2F3
Molecular Weight	229.03 g/mol
Synonyms	3-(Chloromethyl)-1-chloro-5-(trifluoromethyl)benzene; 1-Chloro-3-chloromethyl-5-trifluoromethylbenzene; 2-Chloro-6-(chloromethyl)-α,α,α-trifluoro-p-xylene; α,α,α-Trifluoro-2,6-bis(chloromethyl)toluene; 5-(Trifluoromethyl)-1,3-bis(chloromethyl)benzene (isomer); Benzene, 1-chloro-3-(chloromethyl)-5-(trifluoromethyl)-; Toluene, α,α,α-trifluoro-2,6-bis(chloromethyl)-
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-(Chloromethyl)-5-(Trifluoromethyl)Benzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.