Description

6-Bromo-5-Chloronicotinaldehyde is a high-purity, multi-functional heterocyclic aldehyde building block essential for advanced organic synthesis. This compound is valued for its reactive aldehyde group and halogen substituents, which enable precise molecular construction in complex chemical environments. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a versatile starting material for constructing complex chelating ligands used in catalysis and material science.
• Functional Material Research: Employed in the creation of organic electronic materials, dyes, and photoactive compounds.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	6-Bromo-5-Chloronicotinaldehyde
CAS No.	1228898-23-4
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	5-Chloro-6-bromonicotinaldehyde; 3-Formyl-5-chloro-6-bromopyridine; 6-Bromo-5-chloro-3-pyridinecarboxaldehyde; 6-Bromo-5-chloropyridine-3-carbaldehyde; 5-Chloro-6-bromopyridine-3-carboxaldehyde; Nicotinaldehyde, 6-bromo-5-chloro-
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Chloronicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.