Description

2-Fluoro-6-(Pyrrolidin-1-Yl)Isonicotinaldehyde is a high-value fluorinated pyridine derivative and a versatile chemical building block. This compound is critical for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by pharmaceutical R&D teams, agrochemical scientists, and specialty chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, especially for kinase inhibitors and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, leveraging the fluorine atom and heterocyclic core for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the research of organic semiconductors, liquid crystals, and other functional organic materials due to its electron-deficient pyridine core.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes to study biological processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated heterocyclic aldehydes.

Basic Information

Product Name	2-Fluoro-6-(Pyrrolidin-1-Yl)Isonicotinaldehyde
CAS No.	1228666-44-1
Molecular Formula	C10H11FN2O
Molecular Weight	194.21 g/mol
Synonyms	2-Fluoro-6-(1-pyrrolidinyl)isonicotinaldehyde; 6-(Pyrrolidin-1-yl)-2-fluoropyridine-4-carbaldehyde; 2-Fluoro-6-(pyrrolidin-1-yl)isonicotinaldehyde; 2-Fluoro-6-pyrrolidin-1-ylpyridine-4-carboxaldehyde; 4-Formyl-2-fluoro-6-(1-pyrrolidinyl)pyridine; 1228666-44-1; 2-Fluoro-6-(pyrrolidin-1-yl)pyridine-4-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Pyrrolidin-1-Yl)Isonicotinaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.