Description

1-(2-(Trimethylsilyl)Furo[3,2-B]Pyridin-6-Yl)-Ethanone is a high-value, organosilicon-substituted heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and functional materials, where its unique fused-ring structure enables precise molecular modifications. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and materials science for creating compounds with tailored electronic and biological properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides that require specific heterocyclic frameworks for enhanced activity.
• Material Science Research: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed as a probe or labeling agent in biochemical studies due to its reactive ketone and silyl-protected functionalities.
• Academic & Industrial R&D: A versatile building block for method development and exploring new chemical spaces in organic synthesis.

Basic Information

Product Name	1-(2-(Trimethylsilyl)Furo[3,2-B]Pyridin-6-Yl)-Ethanone
CAS No.	1228666-31-6
Molecular Formula	C₁₄H₁₇NO₂Si
Molecular Weight	259.38 g/mol
Synonyms	6-Acetyl-2-(trimethylsilyl)furo[3,2-b]pyridine; 1-[2-(Trimethylsilyl)furo[3,2-b]pyridin-6-yl]ethanone; Ethanone, 1-[2-(trimethylsilyl)furo[3,2-b]pyridin-6-yl]-; 2-Trimethylsilyl-6-acetylfuro[3,2-b]pyridine; TMS-Furopyridinyl Ethanone; CAS 1228666-31-6
EINECS	Contact for details

Quality Control

Our production of 1-(2-(Trimethylsilyl)Furo[3,2-B]Pyridin-6-Yl)-Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.