Description

(S)-2-(2-Fluorophenyl)Piperidine CAS NO 1228559-38-3 is a high-purity chiral piperidine derivative, a key building block in modern pharmaceutical research and development. Its value lies in its specific stereochemistry and fluorine substitution, which are critical for modulating the biological activity, metabolic stability, and binding affinity of new drug candidates. This compound is essential for medicinal chemists and process development scientists working in the discovery and synthesis of novel therapeutics, particularly within central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities, especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Serves as a chiral ligand precursor or a building block in catalytic asymmetric transformations.
• Preclinical Development: Employed in the scale-up synthesis of compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Utilized in the development of tool compounds for target validation and pathway analysis.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(S)-2-(2-Fluorophenyl)Piperidine
CAS No.	1228559-38-3
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	(S)-2-(2-Fluorophenyl)piperidine; (2S)-2-(2-Fluorophenyl)piperidine; (S)-2-(o-Fluorophenyl)piperidine; (S)-2-(2-Fluorophenyl)piperidine hydrochloride; 2-Fluorophenylpiperidine, (S)-; (S)-2-(2-Fluorophenyl)piperidine free base; (S)-2-(2-Fluorophenyl)azepane (incorrect but common search variant); 1228559-38-3
EINECS	Contact for details

Quality Control

Our (S)-2-(2-Fluorophenyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.