Description

1H-Indole-3-Carbaldehyde is a versatile heterocyclic aromatic aldehyde that serves as a critical building block in advanced organic synthesis. Its unique indole scaffold and reactive formyl group make it an indispensable intermediate for constructing complex molecular architectures. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of indole-based drug candidates, including kinase inhibitors, serotonin receptor modulators, and anti-cancer agents.
• Agrochemical Synthesis: Building block for developing novel pesticides, herbicides, and plant growth regulators that leverage the indole structure for biological activity.
• Material Science Research: Used in the creation of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs) due to its electron-rich aromatic system.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of fluorescent probes, tags, and molecular sensors.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic chemistry, including cross-coupling reactions and heterocyclic chemistry studies.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other specialty chemicals where the indole core provides specific color or functional properties.

Basic Information

Product Name	1H-Indole-3-Carbaldehyde
CAS No.	1228547-52-1
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	Indole-3-carboxaldehyde; 3-Formylindole; 3-Indolecarboxaldehyde; 1H-Indole-3-carboxaldehyde; 3-Indolylcarboxaldehyde; Indol-3-yl-methanal; 3-Formyl-1H-indole; 1H-Indole-3-aldehyde
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates. Specifications can be tailored to support your specific R&D or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	194 - 198 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.