Description

Boronic Acid, B-[4'-(1,1-Dimethylethyl)[1,1'-Biphenyl]-2-Yl]- is a specialized organoboron compound, CAS NO 1228458-46-5, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing sterically hindered biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific biphenyl architectures.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing sophisticated ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on new cross-coupling methodologies and complex molecule assembly.
• Fine Chemical Production: Employed in the custom synthesis of high-value, complex organic molecules for various specialty chemical applications.

Basic Information

Product Name	Boronic Acid, B-[4'-(1,1-Dimethylethyl)[1,1'-Biphenyl]-2-Yl]-
CAS No.	1228458-46-5
Molecular Formula	C18H21BO2
Molecular Weight	280.17 g/mol
Synonyms	2-(4'-tert-Butylbiphenyl-2-yl)boronic acid; [1,1'-Biphenyl]-2-boronic acid, 4'-(1,1-dimethylethyl)-; 4'-tert-Butyl-2-biphenylboronic acid; 4'-tert-Butylbiphenyl-2-ylboronic acid; 2-(4'-tert-Butyl-[1,1'-biphenyl]-2-yl)boronic acid; B-[4'-(tert-Butyl)[1,1'-biphenyl]-2-yl]boronic acid; 2-Borono-4'-tert-butylbiphenyl
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[4'-(1,1-Dimethylethyl)[1,1'-Biphenyl]-2-Yl]- is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for critical synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, supporting compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.