Description

3-(Dimethylamino)-2-Iodoacrolein is a versatile and highly functionalized iodoacrolein derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-donating dimethylamino group and an electrophilic iodoalkene moiety, makes it a valuable precursor for constructing complex heterocycles and pharmaceutical intermediates. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce functional complexity into target molecules with high precision.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Used in the development of advanced organic materials, including functional polymers and liquid crystals.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Heck, Sonogashira) for carbon-carbon bond formation.
• Cyclization Reactions: Facilitates the construction of pyrrole, pyridine, and other nitrogen-containing ring systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	3-(Dimethylamino)-2-Iodoacrolein
CAS No.	1228184-62-0
Molecular Formula	C5H8INO
Molecular Weight	225.03 g/mol
Synonyms	2-Iodo-3-(dimethylamino)acrolein; (E)-2-Iodo-3-(dimethylamino)acrylaldehyde; 3-(Dimethylamino)-2-iodoprop-2-enal; (2E)-2-Iodo-3-(dimethylamino)prop-2-enal; N,N-Dimethyl-2-iodo-3-oxoprop-1-en-1-amine; Iodoacrolein dimethylamino derivative
EINECS	Contact for details

Quality Control

Our 3-(Dimethylamino)-2-Iodoacrolein is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.