Description

4-(Benzylamino)Phenylboronic Acid is a specialized boronic acid derivative that serves as a valuable building block in modern synthetic chemistry. Its bifunctional structure, featuring both a boronic acid group and a benzylamino substituent, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling reactions and the development of bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its coupling capabilities.
• Material Science Research: Employed in the creation of advanced organic materials, including polymers and liquid crystals, where its functional groups enable precise molecular assembly.
• Suzuki-Miyaura Cross-Coupling: Acts as a critical boron-containing partner in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds, a cornerstone of modern organic synthesis.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and sensors that target specific biological pathways or structures.
• Catalyst Ligand Preparation: Serves as a starting material for the synthesis of novel ligands used in homogeneous catalysis.

Basic Information

Product Name	4-(Benzylamino)Phenylboronic Acid
CAS No.	1228183-42-3
Molecular Formula	C₁₃H₁₄BNO₂
Molecular Weight	227.07 g/mol
Synonyms	4-(Benzylamino)benzeneboronic Acid; [4-(Benzylamino)phenyl]boronic Acid; B-[4-(Benzylamino)phenyl]boronic Acid; 4-(Benzylamino)phenylboronic Acid Pinacol Ester (protected form); N-Benzyl-4-boronylaniline; 4-(N-Benzylamino)phenylboronic Acid; 4-(Benzylamino)benzeneboronic acid; (4-(Benzylamino)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-(Benzylamino)Phenylboronic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.