Description

Oxfendazole-D3 (Fenbendazole Sulfoxide-D3) is a deuterium-labeled internal standard of the broad-spectrum anthelmintic agent oxfendazole, essential for ensuring analytical accuracy and reliability in quantitative research. This stable isotope-labeled compound is critical for applications requiring high precision, such as pharmacokinetic studies and residue analysis, where it compensates for matrix effects and instrument variability. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities engaged in veterinary drug development and food safety monitoring.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the accurate measurement of oxfendazole and fenbendazole residues.
• Veterinary Pharmaceutical Research: Facilitates metabolism and pharmacokinetic (PK/PD) studies of benzimidazole anthelmintics in target animal species.
• Food Safety & Residue Testing: Enables precise monitoring of drug residues in meat, milk, and other animal-derived food products to ensure compliance with maximum residue limits (MRLs).
• Bioanalytical Method Development: Serves as a critical component in developing and validating robust analytical methods for regulatory submission.
• Environmental Fate Studies: Aids in tracing the environmental degradation and transformation pathways of anthelmintic drugs.
• Clinical Research: Supports human clinical trials investigating repurposed applications of benzimidazole compounds.
• Quality Control in Manufacturing: Acts as a reference material for the quality assurance of active pharmaceutical ingredients (APIs) and finished drug products.

Basic Information

Product Name	Oxfendazole-D3 (Fenbendazole Sulfoxide-D3)
CAS No.	1228182-54-4
Molecular Formula	C15H10D3N3O3S
Molecular Weight	318.37 g/mol (approximate)
Synonyms	Fenbendazole Sulfoxide-d3; [2H3]-Oxfendazole; Methyl 5-(phenylsulfinyl)-1H-benzimidazol-2-ylcarbamate-d3; 5-Phenylsulfinyl-2-benzimidazolecarbamic Acid Methyl Ester-d3; Oxfendazole (methyl-d3); Oxfendazole Internal Standard; Fenbendazole Sulfoxide (methyl-d3); Deuterated Oxfendazole
EINECS	Contact for details

Quality Control

Our deuterated standards are manufactured under strict quality systems to ensure the highest isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic techniques, including NMR and high-resolution mass spectrometry (HRMS). Certificates of Analysis (COA) are provided, detailing parameters such as chemical purity, isotopic enrichment, and chromatographic profile. We support compliance with GMP/GLP guidelines for research use.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (deuterium)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.