Description

(2-Benzyl-1,2,3,4-Tetrahydrobenzo[B][1,6]Naphthyridin-10-Yl)(4-Methylpiperazin-1-Yl)Methanone is a high-purity, complex organic compound featuring a fused tetracyclic benzo[b][1,6]naphthyridine core, which is of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological intermediate or reference standard for the synthesis and study of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and contract research organizations (CROs) engaged in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and other complex disease pathways.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, particularly those targeting kinase inhibition or receptor modulation.
• Biochemical Research: Used as a reference standard or probe compound in high-throughput screening (HTS) assays to identify and validate new biological targets.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead molecules.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis methodology and heterocyclic chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of clinical trial materials.
• Analytical Standard: Provides a certified reference material for quality control and method development in analytical laboratories using HPLC, LC-MS, or NMR.

Basic Information

Product Name	(2-Benzyl-1,2,3,4-Tetrahydrobenzo[B][1,6]Naphthyridin-10-Yl)(4-Methylpiperazin-1-Yl)Methanone
CAS No.	1228168-13-5
Molecular Formula	C25H27N3O
Molecular Weight	385.50 g/mol
Synonyms	(2-Benzyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridin-10-yl)-(4-methylpiperazin-1-yl)methanone; (2-Benzyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridin-10-yl)(4-methyl-1-piperazinyl)methanone; (2-Benzyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridin-10-yl)(4-methylpiperazin-1-yl)methanone; Methanone, (2-benzyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridin-10-yl)(4-methyl-1-piperazinyl)-; 1228168-13-5; Benzonaphthyridine derivative; Tetracyclic piperazine amide
EINECS	Contact for details

Quality Control

Our production of (2-Benzyl-1,2,3,4-Tetrahydrobenzo[B][1,6]Naphthyridin-10-Yl)(4-Methylpiperazin-1-Yl)Methanone adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is fully characterized by advanced analytical techniques including HPLC, 1H/13C NMR, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and opened in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.