Description

Chloro[[1,3-Bis(2,6-Diisopropylphenyl)Imidazol-2-Ylidene](Acetanilide)Palladium(II)] is a highly specialized, well-defined N-heterocyclic carbene (NHC) palladium(II) complex designed for advanced catalytic applications. This compound matters for its exceptional stability and selectivity, offering superior performance in demanding cross-coupling reactions compared to traditional phosphine-based catalysts. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing complex organic molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination, Suzuki-Miyaura, and other C–N/C–C cross-coupling reactions in API development.
• Agrochemical Research: Enables the efficient construction of complex heterocyclic structures found in novel active ingredients.
• Materials Science: Used in the synthesis of conjugated polymers, organic semiconductors, and specialty monomers.
• Methodology Development: A preferred catalyst in academic and industrial R&D for developing new synthetic protocols under mild conditions.
• Scale-up Process Chemistry: Suitable for optimizing and scaling coupling reactions from lab to pilot plant due to its robustness.
• Fine Chemical Production: Catalyzes the synthesis of high-value, structurally complex fragrance and flavor intermediates.

Basic Information

Product Name	Chloro[[1,3-Bis(2,6-Diisopropylphenyl)Imidazol-2-Ylidene](Acetanilide)Palladium(II)]
CAS No.	1228009-69-5
Molecular Formula	C35H45ClN3OPd
Molecular Weight	672.61 g/mol
Synonyms	Palladium, chloro[2-[(2,6-bis(1-methylethyl)phenyl)amino]-N-(2,6-bis(1-methylethyl)phenyl)-α-keto-1H-imidazol-1-yl-κC2]-, (SP-4-2)-; (NHC)Pd(acetanilide)Cl complex; Pd PEPPSI-type complex with acetanilide ligand; Acetanilide-ligated NHC-Pd(II) chloride; [Pd(IPr)(acetanilide)Cl]; Palladium(II) NHC-acetanilide complex; Chloro(acetanilido)(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)palladium
EINECS	Contact for details

Quality Control

Our Chloro[[1,3-Bis(2,6-Diisopropylphenyl)Imidazol-2-Ylidene](Acetanilide)Palladium(II)] is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot is characterized by NMR, HPLC, and elemental analysis to verify identity, purity, and the absence of deleterious impurities like palladium black or ligand oxides. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Palladium (Pd) Content	15.5 - 16.5 %
Solubility	Soluble in dichloromethane, THF; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.