Description

2-{[4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Benzaldehyde is a high-value, multifunctional chemical building block featuring a benzaldehyde core linked to a trifluoromethyl-substituted pyrimidine ring via an ether bond. This compound matters for its unique structural motif, which combines the electrophilic aldehyde group with the electron-deficient, bioisosteric trifluoromethylpyrimidine moiety, enabling precise molecular design in advanced synthesis. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of herbicides, fungicides, and pharmaceutical intermediates targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting enzyme inhibition where the pyrimidine scaffold is critical.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, leveraging the biological activity of the trifluoromethylpyrimidine group.
• Organic Electronic Materials: Acts as a building block for constructing complex organic molecules used in materials science research, such as ligands for catalysts or components for organic semiconductors.
• Chemical Biology Probes: Utilized in developing molecular probes and tags for studying biological processes due to its reactive aldehyde handle for bioconjugation.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific fluorinated heterocyclic aldehyde.

Basic Information

Product Name	2-{[4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Benzaldehyde
CAS No.	1227954-93-9
Molecular Formula	C₁₂H₇F₃N₂O₂
Molecular Weight	268.19 g/mol
Synonyms	2-((4-(Trifluoromethyl)pyrimidin-2-yl)oxy)benzaldehyde; Benzaldehyde, 2-[[4-(trifluoromethyl)-2-pyrimidinyl]oxy]-; 2-[[4-(Trifluoromethyl)pyrimidin-2-yl]oxy]benzaldehyde; 2-(4-Trifluoromethyl-pyrimidin-2-yloxy)-benzaldehyde; 2-[(4-Trifluoromethylpyrimidin-2-yl)oxy]benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-{[4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.