Description

Benzyl 2-Formyl-7-Azaspiro[3.5]Nonane-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic and formyl-substituted structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Utilized in the construction of bifunctional molecules designed for targeted protein degradation.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	Benzyl 2-Formyl-7-Azaspiro[3.5]Nonane-7-Carboxylate
CAS No.	1227610-18-5
Molecular Formula	C17H19NO3
Molecular Weight	285.34 g/mol
Synonyms	7-(Benzyloxycarbonyl)-2-formyl-7-azaspiro[3.5]nonane; Benzyl 2-formyl-7-azaspiro[3.5]nonane-7-carboxylate; 2-Formyl-7-azaspiro[3.5]nonane-7-carboxylic acid benzyl ester; 7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-formyl-, benzyl ester; 1227610-18-5; Cbz-protected 2-formyl-7-azaspiro[3.5]nonane
EINECS	Contact for details

Quality Control

Our Benzyl 2-Formyl-7-Azaspiro[3.5]Nonane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.