Description

3-Bromo-5-Fluoropyridine-2-Carbaldehyde is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and fluorine substituents adjacent to a reactive aldehyde group, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated pyridine motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes due to its reactive aldehyde handle.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom synthesis services and scale-up production for clinical trial materials.

Basic Information

Product Name	3-Bromo-5-Fluoropyridine-2-Carbaldehyde
CAS No.	1227603-05-5
Molecular Formula	C6H3BrFNO
Molecular Weight	204.00 g/mol
Synonyms	2-Bromo-6-fluoropyridine-3-carboxaldehyde; 5-Fluoro-3-bromopicolinaldehyde; 3-Bromo-5-fluoropicolinaldehyde; 2-Formyl-3-bromo-5-fluoropyridine; 3-Bromo-5-fluoro-2-pyridinecarboxaldehyde; 1227603-05-5; 3-Bromo-5-fluoropyridine-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Fluoropyridine-2-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure high purity and consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.