Description

5-Bromo-2-Fluoropyridine-4-Carbaldehyde is a versatile and high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents adjacent to an aldehyde group, makes it a valuable precursor for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials, liquid crystals, and polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Aldehyde Functionalization: The reactive aldehyde group allows for further derivatization via condensation, reduction, or nucleophilic addition to create diverse chemical libraries.

Basic Information

Product Name	5-Bromo-2-Fluoropyridine-4-Carbaldehyde
CAS No.	1227588-77-3
Molecular Formula	C6H3BrFNO
Molecular Weight	204.00 g/mol
Synonyms	4-Formyl-5-bromo-2-fluoropyridine; 2-Fluoro-5-bromo-4-pyridinecarboxaldehyde; 5-Bromo-2-fluoro-4-formylpyridine; 5-Bromo-2-fluoroisonicotinaldehyde; 5-Bromo-2-fluoropyridine-4-carboxaldehyde; 2-Fluoro-5-bromopyridine-4-carbaldehyde; 4-Pyridinecarboxaldehyde, 5-bromo-2-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoropyridine-4-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.