Description

3-Chloro-5-Fluoropyridine-2-Carbaldehyde is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents adjacent to a reactive aldehyde group, makes it an indispensable precursor for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Development: Used in creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine core.
• Ligand and Catalyst Synthesis: Serves as a precursor for manufacturing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.
• Academic & R&D Laboratories: Utilized in methodological studies and the discovery of new chemical reactions involving halogenated aldehydes.

Basic Information

Product Name	3-Chloro-5-Fluoropyridine-2-Carbaldehyde
CAS No.	1227563-32-7
Molecular Formula	C6H3ClFNO
Molecular Weight	159.54 g/mol
Synonyms	2-Formyl-3-chloro-5-fluoropyridine; 3-Chloro-5-fluoro-2-pyridinecarboxaldehyde; 3-Chloro-5-fluoropyridine-2-carboxaldehyde; 5-Fluoro-3-chloropyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 3-chloro-5-fluoro-; 3-Chloro-5-fluoro-2-formylpyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoropyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development under ISO guided standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.