Description

3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carbaldehyde is a high-purity fluorinated pyridine derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a reactive aldehyde group with electron-withdrawing fluorine and trifluoromethyl substituents, enabling precise functionalization for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carbaldehyde
CAS No.	1227499-98-0
Molecular Formula	C7H3F4NO
Molecular Weight	193.10 g/mol
Synonyms	2-Formyl-3-fluoro-5-(trifluoromethyl)pyridine; 3-Fluoro-5-trifluoromethyl-2-pyridinecarboxaldehyde; 3-Fluoro-5-(trifluoromethyl)picolinaldehyde; 2-Pyridinecarboxaldehyde, 3-fluoro-5-(trifluoromethyl)-; 3-Fluoro-5-(trifluoromethyl)-2-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.