Description

5-Bromo-3-(trifluoromethyl)-2-pyridinecarboxaldehyde is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both bromine and trifluoromethyl substituents, makes it an essential precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of functional organic materials, such as liquid crystals and organic light-emitting diodes (OLEDs), due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	5-Bromo-3-(trifluoromethyl)-2-pyridinecarboxaldehyde
CAS No.	1227489-83-9
Molecular Formula	C7H3BrF3NO
Molecular Weight	253.00 g/mol
Synonyms	5-Bromo-3-(trifluoromethyl)picolinaldehyde; 2-Pyridinecarboxaldehyde, 5-bromo-3-(trifluoromethyl)-; 5-Bromo-3-trifluoromethylpyridine-2-carbaldehyde; 5-Bromo-3-(trifluoromethyl)-2-formylpyridine; 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-(trifluoromethyl)-2-pyridinecarboxaldehyde adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.