Description

1-(Phenylsulphonyl)-5-Methyl-7-Azaindole-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique azaindole core functionalized with a phenylsulfonyl group and an aldehyde moiety. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted small-molecule therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other biologically active compounds for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the generation of novel compound libraries.
• API Development: Used in the research and process development stages for new active pharmaceutical ingredients (APIs), particularly in oncology.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and for high-throughput screening campaigns.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.

Basic Information

Product Name	1-(Phenylsulphonyl)-5-Methyl-7-Azaindole-2-Carbaldehyde
CAS No.	1227270-57-6
Molecular Formula	C₁₇H₁₄N₂O₃S
Molecular Weight	326.37 g/mol
Synonyms	1-(Phenylsulfonyl)-5-methyl-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde; 5-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxaldehyde; 1H-Pyrrolo[2,3-b]pyridine-2-carboxaldehyde, 5-methyl-1-(phenylsulfonyl)-; 1-(Benzenesulfonyl)-5-methyl-7-azaindole-2-carbaldehyde; 5-Methyl-1-tosyl-7-azaindole-2-carbaldehyde (common); 1-(Phenylsulfonyl)-5-methyl-7-aza-indole-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-5-Methyl-7-Azaindole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.