Description

1-(Phenylsulfonyl)-4-Azaindole-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique azaindole core functionalized with a phenylsulfonyl group and an aldehyde moiety. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel, biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small-molecule drug candidates, particularly for oncology and anti-inflammatory targets.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing potent and selective kinase inhibitors due to its azaindole structure.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	1-(Phenylsulfonyl)-4-Azaindole-2-Carbaldehyde
CAS No.	1227269-10-4
Molecular Formula	C15H10N2O3S
Molecular Weight	298.32 g/mol
Synonyms	1-(Benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxaldehyde; 1H-Pyrrolo[2,3-b]pyridine-2-carboxaldehyde, 1-(phenylsulfonyl)-; 4-Azaindole-2-carbaldehyde, 1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-4-Azaindole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.