Description

1-(Phenylsulfonyl)-6-Azaindole-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonylated azaindole scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology and inflammatory diseases.
• Kinase Inhibitor Synthesis: Serves as a core structural motif in the design and synthesis of potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs in academic and industrial R&D labs.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	1-(Phenylsulfonyl)-6-Azaindole-2-Carbaldehyde
CAS No.	1227266-97-8
Molecular Formula	C15H10N2O3S
Molecular Weight	298.32 g/mol
Synonyms	6-Azaindole-2-carbaldehyde, 1-(phenylsulfonyl)-; 1-(Benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde; 1H-Pyrrolo[2,3-b]pyridine-2-carbaldehyde, 1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-6-Azaindole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.