Description

n-Acetyl-3,4-Dihydropyridine-5-Boronic Ester is a specialized organoboron building block, specifically a boronic ester derivative of a dihydropyridine scaffold. This compound is of significant value in modern synthetic chemistry, particularly in cross-coupling reactions, due to the versatility of the boronic ester functional group. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting cardiovascular and neurological pathways.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial coupling partner for the formation of carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the dihydropyridine core for biological activity.
• Material Science Precursor: Employed in the research and development of organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Process Chemistry & Scale-up: Provides a reliable and scalable intermediate for the production of target molecules at pilot and commercial scales.

Basic Information

Product Name	n-Acetyl-3,4-Dihydropyridine-5-Boronic Ester
CAS No.	1227068-63-4
Molecular Formula	C9H12BNO3 (Contact for details on specific ester)
Molecular Weight	Contact for details
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carbaldehyde; 1-Acetyl-1,2,3,6-tetrahydropyridine-5-boronic acid pinacol ester; 5-Boronic ester of 1-acetyl-1,2,3,6-tetrahydropyridine; 5-(Pinacolatoboryl)-3,4-dihydro-2H-pyridine-1-carbaldehyde; n-Acetyl-δ3-piperideine-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-3,4-Dihydropyridine-5-Boronic Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and process applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Contact for higher grades)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.