Description

2-Quinolinyl-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel quinoline-based active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new crop protection agents and herbicides.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the development of chemical probes.
• Catalyst Ligand Synthesis: Serves as a starting material for preparing sophisticated ligands used in homogeneous catalysis.
• Academic & Contract Research: A valuable reagent for methodological development and library synthesis in academic and CRO laboratories.

Basic Information

Product Name	2-Quinolinyl-Boronic Acid Pinacol Ester
CAS No.	1226995-21-6
Molecular Formula	C₁₅H₁₈BNO₂
Molecular Weight	255.12 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; Quinolin-2-ylboronic Acid Pinacol Ester; 2-Quinolineboronic Acid Pinacol Ester; 2-(Pinacolboranyl)quinoline; 2-Quinolylboronic Acid Pinacol Ester; 2-Quinolinylboronic Acid, Pinacol Ester; B-(2-Quinolinyl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-Quinolinyl-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.