Description

Ethyl 4-(5-Fluoro-2-Methoxyphenyl)-2,4-Dioxobutanoate CAS NO 1225574-45-7 is a high-purity, specialized organic intermediate featuring a β-diketone ester structure with a fluorinated aromatic moiety. This compound is critical for advanced synthetic chemistry, enabling the precise construction of complex molecular architectures. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or monomers for specialty polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and cellular pathways.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge research in medicinal and synthetic organic chemistry.

Basic Information

Item	Detail
Product Name	Ethyl 4-(5-Fluoro-2-Methoxyphenyl)-2,4-Dioxobutanoate
CAS No.	1225574-45-7
Molecular Formula	C₁₃H₁₃FO₅
Molecular Weight	268.24 g/mol
Synonyms	Ethyl 4-(5-Fluoro-2-methoxyphenyl)-2,4-dioxobutanoate; 4-(5-Fluoro-2-methoxyphenyl)-2,4-dioxobutanoic Acid Ethyl Ester; 2,4-Dioxo-4-(5-fluoro-2-methoxyphenyl)butanoic Acid Ethyl Ester; 5-Fluoro-2-methoxyphenyl Dioxobutanoate Ethyl Ester; Ethyl (5-Fluoro-2-methoxyphenyl)dioxobutanoate; 1225574-45-7; Acetoacetic ester derivative
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-(5-Fluoro-2-Methoxyphenyl)-2,4-Dioxobutanoate is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.