Description

(1,1-Dioxidotetrahydro-2H-Thiopyran-4-Yl)Acetic Acid(Saltdata: Free) CAS NO 1224869-02-6 is a high-purity, advanced pharmaceutical intermediate characterized by its sulfone-containing heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drug candidates with improved efficacy and safety profiles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Sulfone Chemistry Research: Serves as a versatile scaffold in medicinal chemistry for exploring structure-activity relationships (SAR) in drug discovery programs.
• Protease Inhibitor Synthesis: Potential use in constructing core structures for inhibitors targeting various protease enzymes.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis or metal-organic frameworks.
• Advanced Material Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers with unique properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Detail
Product Name	(1,1-Dioxidotetrahydro-2H-Thiopyran-4-Yl)Acetic Acid (Saltdata: Free)
CAS No.	1224869-02-6
Molecular Formula	C7H12O4S
Molecular Weight	192.23 g/mol
Synonyms	4-(Carboxymethyl)tetrahydro-2H-thiopyran 1,1-dioxide; Tetrahydro-2H-thiopyran-4-acetic acid, 1,1-dioxide; (Tetrahydro-2H-thiopyran-4-yl)acetic acid S,S-dioxide; (1,1-Dioxo-1λ⁶-thian-4-yl)acetic acid; 1,1-Dioxothian-4-ylacetic acid; (1,1-Dioxotetrahydro-2H-thiopyran-4-yl)acetic acid; Contact for additional trade names or abbreviations.
EINECS	Contact for details

Quality Control

Our (1,1-Dioxidotetrahydro-2H-Thiopyran-4-Yl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) documenting full specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.