Description

2-Aminobenzo[D]Oxazol-5-Ylboronic Acid Hydrochloride is a specialized boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures, particularly through Suzuki-Miyaura cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Agrochemical Development: Used in constructing complex molecules for next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLEDs and conductive polymers.
• Suzuki-Miyaura Cross-Coupling: The quintessential application, facilitating carbon-carbon bond formation to create biaryl and heterobiaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Ligand Synthesis: Acts as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Aminobenzo[D]Oxazol-5-Ylboronic Acid Hydrochloride
CAS No.	1224844-65-8
Molecular Formula	C7H7BBrN2O2 • HCl
Molecular Weight	270.31 g/mol (Free base: 233.76 g/mol)
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2-amine hydrochloride; 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoxazole hydrochloride; 2-Aminobenzoxazol-5-ylboronic acid, pinacol ester, hydrochloride; B-(2-Amino-5-benzoxazolyl)boronic acid hydrochloride; 1224844-65-8; Benzo[d]oxazol-2-amine, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Aminobenzo[D]Oxazol-5-Ylboronic Acid Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your R&D and cGMP-compliant production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) when possible to ensure long-term stability. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.