Description

3-[(E)-(2-Fluorophenyl)Methylidene]-2,3-Dihydro-4H-Chromen-4-One is a specialized fluorinated chromenone derivative, a key structural motif in advanced organic synthesis. This compound matters as a versatile pharmaceutical intermediate and research chemical for developing novel active molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the bioactivity of the chromenone scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor or core structure in the synthesis of advanced organic electronic materials due to its conjugated system.
• Fluorescent Probe Synthesis: Utilized in creating molecular probes for bioimaging and diagnostic applications, where the fluorinated aromatic group can modulate photophysical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.
• Ligand Development: Investigated as a potential scaffold for creating novel ligands in catalytic and medicinal chemistry.

Basic Information

Product Name	3-[(E)-(2-Fluorophenyl)Methylidene]-2,3-Dihydro-4H-Chromen-4-One
CAS No.	1224712-84-8
Molecular Formula	C16H11FO2
Molecular Weight	254.26 g/mol
Synonyms	(E)-3-(2-Fluorobenzylidene)chroman-4-one; 3-[(E)-2-Fluorobenzylidene]-4-chromanone; 2H-1-Benzopyran-4-one, 3-[(E)-(2-fluorophenyl)methylene]-2,3-dihydro-; 3-(2-Fluorobenzylidene)chroman-4-one; 4H-Chromen-4-one, 3-[(E)-(2-fluorophenyl)methylene]-2,3-dihydro-; FL-chromanone derivative; Fluorinated chromenone intermediate
EINECS	Contact for details

Quality Control

Our 3-[(E)-(2-Fluorophenyl)Methylidene]-2,3-Dihydro-4H-Chromen-4-One is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.